### GEORGE MASON
UNIVERSITY

DEPARTMENT OF MATHEMATICAL
SCIENCES

APPLIED AND COMPUTATIONAL MATHEMATICS SEMINAR

**Speaker:**Edwin R. Fuller, Jr.,
National Institute of Standards and Technology, Gaithersburg, MD 20899

**Title: ***
Mesoscale Computer Simulations:
from exploding ceramics to tumor ablation
*

**Abstract:**
Characterizing the physical behavior of complex heterogeneous systems is not
straightforward, especially when the constituent components are micrometer to
nanometer in size. Analytical models, while useful, are restricted by their
simplifying assumptions. Experimental measurements of physical properties and
behavior likewise are subject to interpretation, especially at small length
scales, and are fraught with experimental uncertainties. Mesoscale computer
simulations provide an alternative stratagem for predicting physical
properties and behavior of complex heterogeneous systems at the small scale.
Several examples are given to illustrate this approach. They range from near-
zero thermal expansion ceramic composites for use in precision optical devices
(e.g., extreme ultraviolet nano-lithography), but which can self-destruct due
to high internal stresses, to optically activated gold-shell nanoparticles for
use in tumor ablation, while leaving the surrounding healthy tissue intact.

**Time:** Friday, February 15, 2007, 1:30-2:30 p.m.
**Place:** Research I, Room 301

Department of Mathematical Sciences

George Mason University

4400 University Drive, MS 3F2

Fairfax, VA 22030-4444

http://math.gmu.edu/

Tel. 703-993-1460, Fax. 703-993-1491