GEORGE MASON UNIVERSITY
DEPARTMENT OF MATHEMATICAL SCIENCES
APPLIED AND COMPUTATIONAL MATHEMATICS SEMINAR


Speaker:Javed Siddique, Penn State - York
Title: Mathematical Modeling of Tear film dynamics

Abstract: We develop a model for the evaporation and breakup up of tear film. This model includes the effects of surface tension, insoluble surfactant monolayer transport, solutal Marangoni effects, evaporation, osmolarity transport, osmosis and wettability of corneal surface. Knowing that the tear film is a complex fluid structure composed of multiple layers: an aqueous layer that comprises most of the film and an outermost thinner lipid layer coat a forest of large transmembrane mucins at the epithelial surface. The glycocalyx helps provide stability to the ocular surface by assisting the tear film to wet it. It is also permeable to water, but less so to ions. We formulate a thin film model based on lubrication theory in order to understand the dynamics between the aqueous layer and the glycocalyx, which we treat as a deformable porous medium. We present numerical solutions of these models and discuss the roles played by the key parameters of the system.

Time: Friday, April 15, 2016, 1:30-2:20 p.m.

Place: Exploratory Hall, Room 4106


Department of Mathematical Sciences
George Mason University
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Fairfax, VA 22030-4444
http://math.gmu.edu/
Tel. 703-993-1460, Fax. 703-993-1491