Speaker: Ira Schwartz, Naval Research Laboratory
Title: The Dynamical Geometry of Epidemic Extinction
Abstract: The control and eradication, or fade-out, of infectious diseases is a penultimate goal for improving public health. In order to promote and design control methods, such as vaccination and social group quarantine, one must determine how the disease spreads dynamically. However, modeling the dynamics of an outbreak includes many complicating features, such as deterministic and stochastic chaotic-like behavior. Such complicated dynamics can enhance the probability of extinction. In large populations, although extinction occurs with probability one, extinction is considered a rare event which maximizes the probability of disease fade-out.
In this talk, we show that the path to extinction possesses a maximal sensitivity to initial conditions which is similar to local measures of chaotic behavior, and may be quantified by computing finite time Lyapunov exponents. As a result, the extinction path emerges naturally from the underlying dynamical geometry and may be constructed explicitly. The theory will be applied to several stochastic epidemiological models.
This work is done in collaboration with Drs. Eric Forgoston,
Simone Bianco, and Leah Shaw, and is supported by the Office of
Naval Research, National Institutes of Health, and Air Force Office of
Time: Friday, Oct. 28, 2011, 1:30-2:30 p.m.
Place: Science and Tech I, Room 242
Department of Mathematical Sciences
George Mason University
4400 University Drive, MS 3F2
Fairfax, VA 22030-4444
Tel. 703-993-1460, Fax. 703-993-1491